Information for Pharmacists

Please see the following information for pharmacists regarding Quillivant XR reconstitution, preparation, dispensing, and instructions for use.

Reconstituting and dispensing Quillivant XR

Quillivant XR is supplied as a powder for oral suspension and MUST be reconstituted with water prior to dispensing. Quillivant XR is already flavored, DO NOT add any additional flavoring.

Preparation

  1. Tap bottle until powder flows freely.
  2. Remove bottle cap and add specified amount of water to bottle. For example, to obtain a 60 mL (300 mg) bottle of Quillivant XR, it MUST be reconstituted with 53 mL of water prior to dispensing. See reconstitution table below.
  3. Fully insert bottle adapter into neck of bottle (see Instructions for Use).
  4. Replace bottle cap.
  5. Shake bottle with vigorous back and forth motion for at least 10 seconds to prepare suspension.

Inserting the bottle adapter

6.  Insert the adapter each time a new bottle is dispensed. The bottle adapter must fit tightly.

Dispense in original container

7.  Dispense in the glass bottle supplied in the product carton. Quillivant XR is stable for up to 4 months after reconstitution when stored at room temperature.

Reconstitution table

Dispense according to instructions

  • Dispensing multiple NDCs results in multiple patient co-pays
  • Dispensing more than 1 bottle when just 1 bottle could be used to fill the script results in higher costs to cash-paying patients and some patients with high-deductible plans

Be prepared for your patient's next visit

  • Before your patient's next refill, check to make sure you have the correct bottle sizes to fill his or her prescription appropriately
  • When stocking Quillivant XR, be sure to review your recent prescriptions to see what was needed. If, due to stocking issues, more than 1 bottle was used to fill a previous prescription when only 1 bottle was needed, consider ordering the appropriate bottle size from your wholesaler for the next anticipated fill

 

Administration

CHECK contents

Step 1. Remove the Quillivant XR bottle and oral dosing dispenser from the box. If the oral dosing dispenser is missing or not provided, please contact your pharmacist for a replacement.

Step 2. Check and make sure that the Quillivant XR bottle contains liquid medicine. If Quillivant XR is still in powder form, do not use it. Return it to your pharmacist.

SHAKE vigorously

Step 3. Shake the bottle well (up and down) for at least 10 seconds before each use.

PREPARE dose

Step 4. Uncap the bottle and check that the bottle adapter has been fully inserted into the bottle. If bottle adapter has not been inserted by the pharmacist into the bottle, insert adapter into the bottle. After the bottle adapter has been fully inserted into the bottle, it should not be removed. If the bottle adapter has not been inserted and is missing from the box, contact your pharmacist.

The bottle adapter must be fully inserted and should be even with the mouth of the bottle and must remain in place to allow the child resistant cap to work the right way.

Step 5. Check the Quillivant XR dose in milliliters (mL) as prescribed by your healthcare professional. Locate this number on the oral dosing dispenser.

Step 6. Insert tip of the oral dosing dispenser into the upright bottle and push the plunger all the way down.

Step 7. With the oral dosing dispenser in place, turn the bottle upside down. Pull the plunger to the number of mL you need (the amount of liquid medicine in Step 5). Measure the number of mL of medicine from the white end of the plunger.

Step 8. Remove the oral dosing dispenser from the bottle adapter.

ADMINISTER Quillivant XR

Step 9. Slowly squirt Quillivant XR directly into your or your child's mouth.

PROPER storage

Step 10. Cap the bottle tightly. Store the bottle upright at 59ºF to 86ºF (15ºC to 30ºC).

Step 11. Clean the oral dosing dispenser after each use by placing in the dishwasher, or by rinsing with tap water.

Remind patients that they must vigorously shake the bottle for at least 10 seconds before each dose, to ensure that the proper dose is administered.








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Co-pay card processing

Note to pharmacist: always process free-trial vouchers and co-pay card through patient's insurance so that deductibles can be properly accounted for.

Use the BIN number highlighted on the bottom left side of the co-pay card shown above.

Please see the following information for pharmacists regarding QuilliChew ER preparation and dosing options.

  • QuilliChew ER is available in 20 mg scored, 30 mg scored, and 40 mg unscored tablets that can be taken with or without food
  • Scored tablet options allow the dose to be titrated up or down weekly in increments of 10 mg15 mg, and 20 mg*

*Prior to treating pediatric patients and adults with CNS stimulants, including QuilliChew ER, assess for the presence of cardiac disease (ie, perform a careful history, family history of sudden death or ventricular arrhythmia, and physical exam). The recommended starting dose is 20 mg given orally once daily in the morning. Dosage may be increased or decreased weekly in increments of 10 mg, 15 mg, or 20 mg per day. Daily dosage above 60 mg is not recommended. Reduce dosage or discontinue therapy if patients exhibit paradoxical aggravation of symptoms or other side effects, or if improvement is not observed after an appropriate dose adjustment over a 1-month period.

Co-pay card processing

Note to pharmacist: always process free-trial vouchers and co-pay card through patient's insurance so that deductibles can be properly accounted for.

Use the BIN number highlighted on the bottom left side of the co-pay card shown above.

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