Dosing Calculators

Dosing and titration calculators

Use the following calculators to determine the bottle size to write for a patient prescription.

 
 
 
 

Prior to treating pediatric patients and adults with CNS stimulants, including Quillivant XR, assess for the presence of cardiac disease (ie, perform a careful history, family history of sudden death or ventricular arrhythmia, and physical exam). Starting dose is 20 mg which can be titrated up or down, weekly, in increments of 10 to 20 mg up to a maximum daily dose of 60 mg. Reduce dosage if a paradoxical aggravation of symptoms or other adverse events occur. Discontinue if intolerable side effects develop or after 1 month if improvement is not seen after appropriate dose adjustments.

Writing a Quillivant XR prescription (1 mL=5 mg)

Prescribing 2 bottles with different NDC codes when just 1 bottle could be used to fill the prescription may result in extra out-of-pocket or co-pay costs for your patients.

As you use these calculators, keep the following in mind:

  • Prior to treating pediatric patients and adults with CNS stimulants, including Quillivant XR, assess for the presence of cardiac disease (ie, perform a careful history, family history of sudden death or ventricular arrhythmia, and physical exam)
  • Quillivant XR MUST be reconstituted with water by a pharmacist
  • After reconstitution by a pharmacist with water, Quillivant XR is an extended-release oral suspension: 25 mg/5 mL (5 mg/mL). The pharmacist must insert bottle adapter into neck of bottle. The bottle MUST be shaken vigorously (up and down) for at least 10 seconds before each use
  • The recommended starting dose of Quillivant XR is 20 mg (4 mL) once daily in the morning with or without food for patients 6 years and above
  • The dose may be titrated weekly in increments of 10 mg (2 mL) to 20 mg (4 mL) up to a 60 mg (12 mL) maximum daily dose
  • The dose should be individualized according to the treatment needs and responses of the patient
  • Patients taking Quillivant XR for maintenance therapy should be reevaluated periodically to assess the long-term usefulness of the drug
  • Reduce dosage or discontinue therapy if patients exhibit paradoxical aggravation of symptoms or other side effects, or if improvement is not observed after an appropriate dose adjustment over a 1-month period

Dosing and titration calculators

Use this calculator to determine the number of tablets to write for a patient prescription.

 
 
 
 

Prior to treating pediatric patients and adults with CNS stimulants, including QuilliChew ER, assess for the presence of cardiac disease (ie, perform a careful history, family history of sudden death or ventricular arrhythmia, and physical exam). The recommended starting dose is 20 mg given orally once daily in the morning. Dosage may be increased or decreased weekly in increments of 10 mg, 15 mg, or 20 mg per day. Daily dosage above 60 mg is not recommended. Reduce dosage or discontinue therapy if patients exhibit paradoxical aggravation of symptoms or other side effects, or if improvement is not observed after an appropriate dose adjustment over a 1-month period.

Writing a QuilliChew ER prescription

When prescribing multiple dosage strengths of QuilliChew ER with different NDC codes, keep in mind:

  • This may result in extra out-of-pocket or co-pay costs for your patients
  • Insurance may cover a prescription for multiple strengths within one 30-day time frame; however, this may require prior authorization or a call to your patient's insurance
  • Prescribers should also consider other factors such as tablet burden when writing a prescription